Second Trimester Support Supplements

Designed for the unique nutritional needs of the second trimester, offering essential support for both you and your growing baby. As you move into the second trimester, your body’s needs evolve. Our prenatal supplements are crafted with key nutrients like omega-3 DHA, folate, and iron to support your body’s increased demands.

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New
Prenatal Multivitamin - needed.

Prenatal Multivitamin

4.8
Rated 4.8 out of 5 stars
2,674 Reviews

22 nutrients in just 3 capsules, delivering 8x more nutrition than the average of leading prenatals, at clinically studied dosages of key nutrients that make all the difference.*

From $34.39/mo
Best Seller
Prenatal Multivitamin Pro - needed.

Prenatal Multivitamin Pro

4.8
Rated 4.8 out of 5 stars
2,674 Reviews

Our most comprehensive prenatal formula: Clinically-studied Prenatal Multivitamin Pro features optimal levels of 26 essential nutrients designed to fight nutritional depletion through fertility, pregnancy, and postpartum.*

From $50.39/mo
Prenatal Iron - needed.

Prenatal Iron

4.9
Rated 4.9 out of 5 stars
340 Reviews

Ferrochel iron has been clinically shown to cause fewer gastrointestinal upsets compared to other forms of iron.*

From $17.59/mo
Best Seller
Prenatal Collagen Protein - needed.

Prenatal Collagen Protein

4.8
Rated 4.8 out of 5 stars
1,333 Reviews

Grass-fed and sustainably sourced hydrolyzed collagen peptides support amino acid needs, pelvic floor health, and healthy hair.*

From $39.99/mo
Hydration Support - needed.

Hydration Support

4.5
Rated 4.5 out of 5 stars
934 Reviews

Electrolytes and trace minerals with a hint of lemon support hydration, occasional nausea, and hydration during breastfeeding without sugar or artificial sweeteners.*

Lemon flavor
From $36.79/mo
Choline+ - needed.

Choline+

4.9
Rated 4.9 out of 5 stars
294 Reviews

Our vegan Choline+ supports baby's brain and cognitive development during pregnancy and after birth.*

From $20.79/mo
Prenatal Pre/Probiotic - needed.

Prenatal Pre/Probiotic

4.9
Rated 4.9 out of 5 stars
508 Reviews

Iron absorption, digestive comfort, and gut + vaginal microbiome support across fertility, pregnancy, and postpartum. Powered by Lactoferrin + clinically-studied strains.* 30B CFUs.

From $47.99/mo
Sleep + Relaxation Support - needed.

Sleep + Relaxation Support

4.6
Rated 4.6 out of 5 stars
347 Reviews

Pregnancy-safe and melatonin-free nutrients, including magnesium and L-Theanine, support a calm mind and optimal sleep quality.*

From $39.99/mo
Seasonal Defense Formula
Immune Support - needed.

Immune Support

4.8
Rated 4.8 out of 5 stars
202 Reviews

Our pregnancy-safe, kid-friendly powder with elderberry includes zinc and clinically studied pre/postbiotics for immune support.*

From $47.99/mo
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The Complete Prenatal Plan - Needed

The Complete Prenatal Plan

4.8
Rated 4.8 out of 5 stars
2,043 Reviews

Our bestselling plan for perinatal nutrition includes a Prenatal Multivitamin, Collagen, Omega-3, Iron, and Pre/Probiotics.*

From $174.33/mo
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The Complete Prenatal Plan Pro (Kenta 3 month Test) - needed.

The Complete Prenatal Plan Pro

4.8
Rated 4.8 out of 5 stars
3,818 Reviews

Our bestselling plan for complete perinatal nutrition, with 12x more nutrition than leading prenatals, includes a Prenatal Multi Pro, Collagen, Omega-3 Pro, Iron, and Pre/Probiotics.*

From $208.33/mo
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Prenatal Vitamins with Iron + DHA Pro - needed.

Prenatal Vitamins with Iron + DHA Pro

4.8
Rated 4.8 out of 5 stars
2,332 Reviews

Our radically better Prenatal Multi Pro paired with Iron and sustainably-sourced Omega-3 for all stages of perinatal health.*

From $114.66/mo
Omega - 3 Pro - needed.

Omega-3 Pro

4.9
Rated 4.9 out of 5 stars
530 Reviews

Our Omega-3 Pro delivers 2,000 mg of DHA+EPA per serving — 4× more than most prenatal omega-3s to optimally support baby's brain development and maternal mood.*

From $39.99/mo
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nutrition badge needed
Prenatal Multivitamin Powder - needed.

Prenatal Multivitamin Powder

4.8
Rated 4.8 out of 5 stars
2,674 Reviews

22 nutrients in just 1 scoop of vanilla flavored powder, delivering 8x more nutrition than the average of leading prenatals, at clinically studied dosages of key nutrients that make all the difference.*

From $42.39/mo

Questions? We have answers.

Thoughtful inquiry is needed.

What supplements do I need in the second trimester?

Second-trimester priorities include iron (for blood volume expansion), omega-3 DHA (for fetal brain development), a comprehensive prenatal multi, collagen protein (for tissue support), and electrolytes for hydration.* Needed's second trimester collection addresses each of these with bioavailable, practitioner-recommended formulations.

Why is iron so important in the second trimester?

Your blood volume increases by 40-50% during pregnancy, with the steepest rise occurring in the second trimester. Iron is required for hemoglobin production to carry oxygen to your baby and your own tissues.* Needed's Prenatal Iron uses bisglycinate chelate—a gentle, highly absorbable form that minimizes digestive side effects.*

When should I start taking omega-3 during pregnancy?

While omega-3s are beneficial throughout pregnancy, they become especially important starting in the second trimester when fetal brain growth accelerates. DHA accumulates rapidly in the developing brain from mid-pregnancy onward. Aim for at least 300 mg DHA daily through supplementation or a combination of diet and supplements.

Can collagen protein help with pregnancy skin changes?

Collagen peptides provide glycine and proline—amino acids your body uses to build and repair connective tissue, including skin. As your belly expands through the second and third trimesters, these amino acids may support skin elasticity.* Needed's Prenatal Collagen Protein is formulated specifically for the demands of pregnancy.

Should I change my prenatal protocol between trimesters?

Many practitioners recommend adjusting your protocol to match shifting demands. The second trimester typically warrants adding or increasing iron and omega-3 DHA as fetal growth accelerates. Needed's trimester-specific collections make this easy by curating the products most relevant to each stage.

Meet The Needed® Standard

Uncompromising Nutrient Levels

Uncompromising Nutrient Levels

Designed to Support Optimal Absorption

Designed to Support Optimal Absorption

 Every Ingredient Vetted by Experts

 Every Ingredient Vetted by Experts

Always Rigorously 3rd Party Tested

Always Rigorously 3rd Party Tested

Backed by Pioneering Science and Clinical Insights

Backed by Pioneering Science and Clinical Insights