First Trimester Supplements

Prenatal supplements designed to support everyday wellness during the first trimester. From foundational prenatal formulas to targeted support options, these products are developed using carefully selected ingredients and a science-informed approach. Each supplement is designed to fit seamlessly into a daily routine and support hydration, sleep, immune health, and overall wellness during the first trimester.

Read More +
Shop by ← All Products Pregnancy 1st Trimester 2nd Trimester 3rd Trimester
Best Seller
nutrition badge needed
Prenatal Multivitamin - needed.

Prenatal Multivitamin

4.7
Rated 4.7 out of 5 stars
3,691 Reviews

22 nutrients in just 3 capsules, delivering 8x more nutrition than the average of leading prenatals†, at clinically studied dosages of key nutrients that make all the difference.*

22 Nutrients HSA/FSA Eligible⁂
From $34.39/mo $42.99/mo
Best Seller
Prenatal Multivitamin Pro - needed.

Prenatal Multivitamin Pro

4.7
Rated 4.7 out of 5 stars
3,691 Reviews

Our most comprehensive prenatal formula: Clinically-studied Prenatal Multivitamin Pro features optimal levels of 26 essential nutrients designed to fight nutritional depletion through fertility, pregnancy, and postpartum.*

26 Nutrients HSA/FSA Eligible⁂
From $50.39/mo $62.99/mo
Prenatal Iron - needed.

Prenatal Iron

4.9
Rated 4.9 out of 5 stars
370 Reviews

Ferrochel iron has been clinically shown to cause fewer gastrointestinal upsets compared to other forms of iron.*

Pregnancy Support Ferrochel Iron HSA/FSA Eligible⁂
From $17.59/mo $21.99/mo
Hydration Support - needed.

Hydration Support

4.5
Rated 4.5 out of 5 stars
980 Reviews

Electrolytes and trace minerals with a hint of lemon support hydration, help ease occasional nausea, and support hydration during breastfeeding — without sugar or artificial sweeteners.*

Electrolytes Trace Minerals HSA/FSA Eligible⁂
Lime flavor
From $36.79/mo $45.99/mo
Best Seller
Prenatal Collagen Protein - needed.

Prenatal Collagen Protein

4.8
Rated 4.8 out of 5 stars
1,512 Reviews

Grass-fed and sustainably sourced hydrolyzed collagen peptides support amino acid needs, pelvic floor health, and healthy hair.*

Hydrolyzed Collagen Pregnancy Safe HSA/FSA Eligible⁂
From $39.99/mo $49.99/mo
Choline+ - needed.

Choline+

4.9
Rated 4.9 out of 5 stars
346 Reviews

Our vegan Choline+ supports baby's brain and cognitive development during pregnancy and after birth.*

Vegan Baby's Development HSA/FSA Eligible⁂
From $20.79/mo $25.99/mo
Prenatal Pre/Probiotic - needed.

Prenatal Pre/Probiotic

4.9
Rated 4.9 out of 5 stars
536 Reviews

Iron absorption, digestive comfort, and gut + vaginal microbiome support across fertility, pregnancy, and postpartum. Powered by Lactoferrin + clinically-studied strains.* 30B CFUs.

Lactoferrin 30B CFUs HSA/FSA Eligible⁂
From $47.99/mo $59.99/mo
Sleep + Relaxation Support - needed.

Sleep + Relaxation Support

4.6
Rated 4.6 out of 5 stars
360 Reviews

Pregnancy-safe and melatonin-free nutrients, including magnesium and L-Theanine, support a calm mind and optimal sleep quality.*

Pregnancy Safe Melatonin Free HSA/FSA Eligible⁂
From $39.99/mo $49.99/mo
Seasonal Defense Formula
Immune Support - needed.

Immune Support

4.8
Rated 4.8 out of 5 stars
208 Reviews

Our pregnancy-safe, kid-friendly powder with elderberry includes zinc and clinically studied pre/postbiotics for immune support.*

Pregnancy Safe HSA/FSA Eligible⁂
From $47.99/mo $59.99/mo
Save 15%
The Complete Prenatal Plan Pro (Kenta 3 month Test) - needed.

The Complete Prenatal Plan Pro

4.8
Rated 4.8 out of 5 stars
4,118 Reviews

Our bestselling plan for complete perinatal nutrition, with 12x more nutrition than leading prenatals, includes a Prenatal Multi Pro, Collagen, Omega-3 Pro, Iron, and Pre/Probiotics.*

Bestseller HSA/FSA Eligible⁂
From $220.00/mo
Save 15%
Prenatal Vitamins with Iron + DHA Pro - needed.

Prenatal Vitamins with Iron + DHA Pro

4.8
Rated 4.8 out of 5 stars
2,550 Reviews

Our radically better Prenatal Multi Pro paired with Iron and sustainably-sourced Omega-3 for all stages of perinatal health.*

HSA/FSA Eligible⁂
From $121.00/mo
Save 15%
The Complete Prenatal Plan - Needed

The Complete Prenatal Plan

4.8
Rated 4.8 out of 5 stars
2,402 Reviews

Our bestselling plan for perinatal nutrition includes a Prenatal Multivitamin, Collagen, Omega-3, Iron, and Pre/Probiotics.*

Bestseller HSA/FSA Eligible⁂
From $184.00/mo
Omega - 3 Pro - needed.

Omega-3 Pro

4.9
Rated 4.9 out of 5 stars
619 Reviews

Our Omega-3 Pro delivers 2,000 mg of DHA+EPA per serving — 4× more than most prenatal omega-3s to optimally support baby's brain development and maternal mood.*

2,000 mg of DHA+EPA HSA/FSA Eligible⁂
From $39.99/mo $49.99/mo
New
nutrition badge needed
Prenatal Multivitamin Powder - needed.

Prenatal Multivitamin Powder

4.7
Rated 4.7 out of 5 stars
3,691 Reviews

22 nutrients in just 1 scoop of vanilla flavored powder, delivering 8x more nutrition than the average of leading prenatals†, at clinically studied dosages of key nutrients that make all the difference.*

22 Nutrients HSA/FSA Eligible⁂
From $42.39/mo $52.99/mo
New
Prenatal Multivitamin Gummy - Needed

Prenatal Multivitamin Gummy

4.5
Rated 4.5 out of 5 stars
85 Reviews

Clinical dosages of key nutrients in 3 gummies. 4x more nutrition than leading prenatals‡ and 8x the leading prenatal gummy.‖

17 Nutrients HSA/FSA Eligible⁂
From $34.39/mo $42.99/mo
New
Save 15%
Prenatal Multivitamin Gummy jar beside the Choline+ jar

Prenatal Multivitamin Gummy and Choline+

4.8
Rated 4.8 out of 5 stars
432 Reviews

Supports foundational prenatal nutrition + helps meet the practitioner recommended choline dose.

HSA/FSA Eligible⁂
From $62.00/mo

Questions? We have answers.

Thoughtful inquiry is needed.

Prioritize a prenatal with methylfolate (not folic acid), standalone choline at 550 mg daily, a pregnancy-safe probiotic for digestive support, and electrolytes if morning sickness is causing fluid loss.* Needed's first trimester collection is built around these specific early-pregnancy priorities.

For many women, yes. Methylfolate is the active form of folate your body uses directly, while folic acid requires conversion, which up to 60% of women do inefficiently due to MTHFR gene variations. Since neural tube closure happens in the first 28 days, using the most bioavailable form matters most during this window.

 Take capsules with food, split doses between morning and evening, and choose formulations with active B6 (pyridoxal-5-phosphate), which research links to occasional nausea relief.* Needed's Prenatal Multi uses small capsules and active nutrient forms that tend to be gentler on sensitive stomachs.

Choline plays a direct role in neural tube closure (which happens within 28 days of conception) and early fetal brain development.* Despite being classified as essential, fewer than 10% of pregnant women reach the recommended 550 mg daily. Many prenatals contain none, making standalone choline critical in the first trimester.

Meet The Needed® Standard

Uncompromising Nutrient Levels

Uncompromising Nutrient Levels

Designed to Support Optimal Absorption

Designed to Support Optimal Absorption

 Every Ingredient Vetted by Experts

 Every Ingredient Vetted by Experts

Always Rigorously 3rd Party Tested

Always Rigorously 3rd Party Tested

Backed by Pioneering Science and Clinical Insights

Backed by Pioneering Science and Clinical Insights

Shop supplements by stage

Prenatal Vitamins
Women's Health
Gut Health
Trying & Planning
Men's Health
Pregnancy
Early Motherhood